There is similar uncertainty around the outbreaks in places like Mongolia and Seychelles, which saw spikes after more than half of the population was fully vaccinated. Deaths rose in both countries, although were still in single or low double digits. Many factors – from a country’s natural immunity, to disease control measures, more transmissible variants, and vaccine effectiveness – were likely at play but it was hard to be sure. A vaccine’s ability to stop the virus from spreading via a level of herd protection also depends on the variants of the virus in circulation. The more transmissible a variant, the greater the proportion of people who need to be vaccinated to see a slowing of spread. Mixing and matching various vaccines could be another way to boost effectiveness, a recent study of Pfizer/BioNTech and AstraZeneca suggest that using one of each together could surpass the immune response from the AstraZeneca course alone.
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